2025 Lexus Rx 350h Hybrid Mpg. Based on 2024 estimates, the rx hybrid leads the luxury midsize suv segment with 36 mpg combined (37 mpg in the city, 34 mpg on the highway). Our 2025 lexus rx 350h trim comparison will help you decide.

The 2025 rx hybrid gets excellent fuel economy for the luxury hybrid suv class and for the midsize luxury suv segment. Our 2025 lexus rx 350h trim comparison will help you decide.